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Neutrophil cytosolic factor 1 : ウィキペディア英語版
Neutrophil cytosolic factor 1

Neutrophil cytosol factor 1 is a protein that in humans is encoded by the ''NCF1'' gene.
== Function ==

The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=653361 )
p47 is vital to the activation of NADPH oxidase. P47 becomes heavily phosphorylated

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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